Whei-Mei Teresa Fan | Toxicology and Cancer Biology

Whei-Mei Teresa Fan

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Publications

531 BioPharm Complex

Position(s):

Professor, Edith D. Gardner Chair in Cancer Research

Affiliation(s):

Toxicology and Cancer Biology

PubMed Publications:

Crooks, DR ;Maio, N.;Lane, AN ;Jarnik, M.;Higashi, RM ;Haller, RG ;Yang, Y.;Fan, TW ;Linehan, WM ;Rouault, TA "Acute loss of iron-sulfur clusters results in metabolic reprogramming and generation of lipid droplets in mammalian cells." The Journal of biological chemistry 293, 21 (2018): 8297-8311. [PubMed Link] | [ Full text ]
Zaytseva, YY ;Rychahou, PG ;Le, AT ;Scott, TL ;Flight, RM ;Kim, JT ;Harris, J.;Liu, J.;Wang, C.;Morris, AJ ;Sivakumaran, TA ;Fan, T.;Moseley, H.;Gao, T.;Lee, EY ;Weiss, HL ;Heuer, TS ;Kemble, G.;Evers, M. "Preclinical evaluation of novel fatty acid synthase inhibitors in primary colorectal cancer cells and a patient-derived xenograft model of colorectal cancer." Oncotarget 9, 37 (2018): 24787-24800. [PubMed Link] | [ Full text ]
Kuperman, RG ;Checkai, RT ;Simini, M.;Phillips, CT ;Higashi, RM ;Fan, TW ;Sappington, K. "Selenium toxicity to survival and reproduction of Collembola and Enchytraeids in a sandy loam soil." Environmental toxicology and chemistry 37, 3 (2018): 846-853. [PubMed Link] | [ Full text ]
Fan, TW ;El-Amouri, SS ;Macedo, JKA ;Wang, QJ ;Song, H.;Cassel, T.;Lane, AN "Stable Isotope-Resolved Metabolomics Shows Metabolic Resistance to Anti-Cancer Selenite in 3D Spheroids versus 2D Cell Cultures." Metabolites 8, 3 (2018): [PubMed Link] | [ Full text ]
Deng, P.;Higashi, RM ;Lane, AN ;Bruntz, RC ;Sun, RC ;Raju, MVR ;Nantz, MH ;Qi, Z.;Fan, TW "Correction: Quantitative profiling of carbonyl metabolites directly in crude biological extracts using chemoselective tagging and nanoESI-FTMS." The Analyst 143, 4 (2018): 999. [PubMed Link] | [ Full text ]
Lane, AN ;Tan, J.;Wang, Y.;Yan, J.;Higashi, RM ;Fan, TW "Probing the metabolic phenotype of breast cancer cells by multiple tracer stable isotope resolved metabolomics." Metabolic engineering 43, Pt B (2017): 125-136. [PubMed Link] | [ Full text ]
Zhao, J.;Li, J.;Fan, TWM ;Hou, SX "Glycolytic reprogramming through PCK2 regulates tumor initiation of prostate cancer cells." Oncotarget 8, 48 (2017): 83602-83618. [PubMed Link] | [ Full text ]
Sun, RC ;Fan, TW ;Deng, P.;Higashi, RM ;Lane, AN ;Le, AT ;Scott, TL ;Sun, Q.;Warmoes, MO ;Yang, Y. "Noninvasive liquid diet delivery of stable isotopes into mouse models for deep metabolic network tracing." Nature communications 8, 1 (2017): 1646. [PubMed Link] | [ Full text ]
Wang, Q.;Zhou, Y.;Rychahou, P.;Fan, TW ;Lane, AN ;Weiss, HL ;Evers, BM "Ketogenesis contributes to intestinal cell differentiation." Cell death and differentiation 24, 3 (2017): 458-468. [PubMed Link] | [ Full text ]
Zhao, J.;Li, J.;Fan, TWM ;Hou, SX "Glycolytic reprogramming through PCK2 regulates tumor initiation of prostate cancer cells." Oncotarget (2017): [PubMed Link] | [ Full text ]
Bruntz, RC ;Lane, AN ;Higashi, RM ;Fan, TW "Exploring cancer metabolism using stable isotope-resolved metabolomics (SIRM)." The Journal of biological chemistry 292, 28 (2017): 11601-11609. [PubMed Link] | [ Full text ]
Yang, Y.;Fan, TW ;Lane, AN ;Higashi, RM "Chloroformate derivatization for tracing the fate of Amino acids in cells and tissues by multiple stable isotope resolved metabolomics (mSIRM)." Analytica chimica acta 976, (2017): 63-73. [PubMed Link] | [ Full text ]
Deng, P.;Higashi, RM ;Lane, AN ;Bruntz, RC ;Sun, RC ;Ramakrishnam Raju, MV ;Nantz, MH ;Qi, Z.;Fan, TW "Quantitative profiling of carbonyl metabolites directly in crude biological extracts using chemoselective tagging and nanoESI-FTMS." The Analyst 143, 1 (2017): 311-322. [PubMed Link] | [ Full text ]
Lane, AN ;Fan, TW "NMR-based Stable Isotope Resolved Metabolomics in systems biochemistry." Archives of biochemistry and biophysics 628, (2017): 123-131. [PubMed Link] | [ Full text ]
Li, J.;Song, J.;Zaytseva, YY ;Liu, Y.;Rychahou, P.;Jiang, K.;Starr, ME ;Kim, JT ;Harris, JW ;Yiannikouris, FB ;Katz, WS ;Nilsson, PM ;Orho-Melander, M.;Chen, J.;Zhu, H.;Fahrenholz, T.;Higashi, RM ;Gao, T.;Morris, AJ ;Cassis, LA ;Fan, TW ;Weiss, HL ;Dobner, PR ;Melander, O.;Jia, J.;Evers, BM "An obligatory role for neurotensin in high-fat-diet-induced obesity." Nature 533, 7603 (2016): 411-5. [PubMed Link] | [ Full text ]
Liu, M.;Luo, F.;Ding, C.;Albeituni, S.;Hu, X.;Ma, Y.;Cai, Y.;McNally, L.;Sanders, MA ;Jain, D.;Kloecker, G.;Bousamra M, 2nd ;Zhang, HG ;Higashi, RM ;Lane, AN ;Fan, TW ;Yan, J. "Correction: Dectin-1 Activation by a Natural Product β-Glucan Converts Immunosuppressive Macrophages into an M1-like Phenotype." Journal of immunology (Baltimore, Md. : 1950) 196, 9 (2016): 3968. [PubMed Link] | [ Full text ]
Lane, AN ;Higashi, RM ;Fan, TW "Preclinical models for interrogating drug action in human cancers using Stable Isotope Resolved Metabolomics (SIRM)." Metabolomics : Official journal of the Metabolomic Society 12, 7 (2016): [PubMed Link] |
Fan, TW ;Warmoes, MO ;Sun, Q.;Song, H.;Turchan-Cholewo, J.;Martin, JT ;Mahan, A.;Higashi, RM ;Lane, AN "Distinctly perturbed metabolic networks underlie differential tumor tissue damages induced by immune modulator β-glucan in a two-case ex vivo non-small-cell lung cancer study." Cold Spring Harbor molecular case studies 2, 4 (2016): a000893. [PubMed Link] | [ Full text ]
Saxena, N.;Maio, N.;Crooks, DR ;Ricketts, CJ ;Yang, Y.;Wei, MH ;Fan, TW ;Lane, AN ;Sourbier, C.;Singh, A.;Killian, JK ;Meltzer, PS ;Vocke, CD ;Rouault, TA ;Linehan, WM "SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery." Journal of the National Cancer Institute 108, 1 (2016): [PubMed Link] | [ Full text ]
Fan, TW ;Lane, AN ;Higashi, RM "Stable Isotope Resolved Metabolomics Studies <i>in Ex Vivo</i> TIssue Slices." Bio-protocol 6, 3 (2016): [PubMed Link] |
Fan, TW ;Lane, AN "Applications of NMR spectroscopy to systems biochemistry." Progress in nuclear magnetic resonance spectroscopy 92-93, (2016): 18-53. [PubMed Link] | [ Full text ]
Saxena, N.;Maio, N.;Crooks, DR ;Ricketts, CJ ;Yang, Y.;Wei, MH ;Fan, TW ;Lane, AN ;Sourbier, C.;Singh, A.;Killian, JK ;Meltzer, PS ;Vocke, CD ;Rouault, TA ;Linehan, WM "SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery." Journal of the National Cancer Institute 108, 1 (2015): [PubMed Link] |
Lane, AN ;Yan, J.;Fan, TW "<sup>13</sup>C Tracer Studies of Metabolism in Mouse Tumor Xenografts." Bio-protocol 5, 22 (2015): [PubMed Link] |
Liu, M.;Luo, F.;Ding, C.;Albeituni, S.;Hu, X.;Ma, Y.;Cai, Y.;McNally, L.;Sanders, MA ;Jain, D.;Kloecker, G.;Bousamra M, 2nd ;Zhang, HG ;Higashi, RM ;Lane, AN ;Fan, TW ;Yan, J. "Dectin-1 Activation by a Natural Product β-Glucan Converts Immunosuppressive Macrophages into an M1-like Phenotype." Journal of immunology (Baltimore, Md. : 1950) 195, 10 (2015): 5055-65. [PubMed Link] | [ Full text ]
Lane, AN ;Arumugam, S.;Lorkiewicz, PK ;Higashi, RM ;Laulhé, S.;Nantz, MH ;Moseley, HN ;Fan, TW "Chemoselective detection and discrimination of carbonyl-containing compounds in metabolite mixtures by 1H-detected 15N nuclear magnetic resonance." Magnetic resonance in chemistry : MRC 53, 5 (2015): 337-43. [PubMed Link] | [ Full text ]
Lane, AN ;Fan, TW "Regulation of mammalian nucleotide metabolism and biosynthesis." Nucleic acids research 43, 4 (2015): 2466-85. [PubMed Link] | [ Full text ]
Sellers, K.;Fox, MP ;Bousamra M, 2nd ;Slone, SP ;Higashi, RM ;Miller, DM ;Wang, Y.;Yan, J.;Yuneva, MO ;Deshpande, R.;Lane, AN ;Fan, TW "Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation." The Journal of clinical investigation 125, 2 (2015): 687-98. [PubMed Link] | [ Full text ]
Tarrado-Castellarnau, M.;Cortés, R.;Zanuy, M.;Tarragó-Celada, J.;Polat, IH ;Hill, R.;Fan, TW ;Link, W.;Cascante, M. "Methylseleninic acid promotes antitumour effects via nuclear FOXO3a translocation through Akt inhibition." Pharmacological research 102, (2015): 218-34. [PubMed Link] | [ Full text ]
Xie, H.;Hanai, J.;Ren, JG ;Kats, L.;Burgess, K.;Bhargava, P.;Signoretti, S.;Billiard, J.;Duffy, KJ ;Grant, A.;Wang, X.;Lorkiewicz, PK ;Schatzman, S.;Bousamra M, 2nd ;Lane, AN ;Higashi, RM ;Fan, TW ;Pandolfi, PP ;Sukhatme, VP ;Seth, P. "Targeting lactate dehydrogenase--a inhibits tumorigenesis and tumor progression in mouse models of lung cancer and impacts tumor-initiating cells." Cell metabolism 19, 5 (2014): 795-809. [PubMed Link] | [ Full text ]
Ren, JG ;Seth, P.;Clish, CB ;Lorkiewicz, PK ;Higashi, RM ;Lane, AN ;Fan, TW ;Sukhatme, VP "Knockdown of malic enzyme 2 suppresses lung tumor growth, induces differentiation and impacts PI3K/AKT signaling." Scientific reports 4, (2014): 5414. [PubMed Link] | [ Full text ]
Gori, SS ;Lorkiewicz, P.;Ehringer, DS ;Belshoff, AC ;Higashi, RM ;Fan, TW ;Nantz, MH "Profiling thiol metabolites and quantification of cellular glutathione using FT-ICR-MS spectrometry." Analytical and bioanalytical chemistry 406, 18 (2014): 4371-9. [PubMed Link] | [ Full text ]
Guin, S.;Pollard, C.;Ru, Y.;Ritterson Lew, C.;Duex, JE ;Dancik, G.;Owens, C.;Spencer, A.;Knight, S.;Holemon, H.;Gupta, S.;Hansel, D.;Hellerstein, M.;Lorkiewicz, P.;Lane, AN ;Fan, TW ;Theodorescu, D. "Role in tumor growth of a glycogen debranching enzyme lost in glycogen storage disease." Journal of the National Cancer Institute 106, 5 (2014): [PubMed Link] | [ Full text ]
Higashi, RM ;Fan, TW ;Lorkiewicz, PK ;Moseley, HN ;Lane, AN "Stable isotope-labeled tracers for metabolic pathway elucidation by GC-MS and FT-MS." Methods in molecular biology (Clifton, N.J.) 1198, (2014): 147-67. [PubMed Link] | [ Full text ]
Mitchell, JM ;Fan, TW ;Lane, AN ;Moseley, HN "Development and in silico evaluation of large-scale metabolite identification methods using functional group detection for metabolomics." Frontiers in genetics 5, (2014): 237. [PubMed Link] | [ Full text ]
Dong, C.;Yuan, T.;Wu, Y.;Wang, Y.;Fan, TW ;Miriyala, S.;Lin, Y.;Yao, J.;Shi, J.;Kang, T.;Lorkiewicz, P.;St Clair, D.;Hung, MC ;Evers, BM ;Zhou, BP "Loss of FBP1 by Snail-mediated repression provides metabolic advantages in basal-like breast cancer." Cancer cell 23, 3 (2013): 316-31. [PubMed Link] | [ Full text ]
Yang, Y.;Lane, AN ;Ricketts, CJ ;Sourbier, C.;Wei, MH ;Shuch, B.;Pike, L.;Wu, M.;Rouault, TA ;Boros, LG ;Fan, TW ;Linehan, WM "Metabolic reprogramming for producing energy and reducing power in fumarate hydratase null cells from hereditary leiomyomatosis renal cell carcinoma." PloS one 8, 8 (2013): e72179. [PubMed Link] | [ Full text ]
Muenyi, CS ;Pinhas, AR ;Fan, TW ;Brock, GN ;Helm, CW ;States, JC "Sodium arsenite ± hyperthermia sensitizes p53-expressing human ovarian cancer cells to cisplatin by modulating platinum-DNA damage responses." Toxicological sciences : an official journal of the Society of Toxicology 127, 1 (2012): 139-49. [PubMed Link] | [ Full text ]
Fan, TW ;Lorkiewicz, PK ;Sellers, K.;Moseley, HN ;Higashi, RM ;Lane, AN "Stable isotope-resolved metabolomics and applications for drug development." Pharmacology & therapeutics 133, 3 (2012): 366-91. [PubMed Link] | [ Full text ]
Liu, W.;Le, A.;Hancock, C.;Lane, AN ;Dang, CV ;Fan, TW ;Phang, JM "Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC." Proceedings of the National Academy of Sciences of the United States of America 109, 23 (2012): 8983-8. [PubMed Link] | [ Full text ]
Fan, TW ;Tan, J.;McKinney, MM ;Lane, AN "Stable Isotope Resolved Metabolomics Analysis of Ribonucleotide and RNA Metabolism in Human Lung Cancer Cells." Metabolomics : Official journal of the Metabolomic Society 8, 3 (2012): 517-527. [PubMed Link] |
Le, A.;Lane, AN ;Hamaker, M.;Bose, S.;Gouw, A.;Barbi, J.;Tsukamoto, T.;Rojas, CJ ;Slusher, BS ;Zhang, H.;Zimmerman, LJ ;Liebler, DC ;Slebos, RJ ;Lorkiewicz, PK ;Higashi, RM ;Fan, TW ;Dang, CV "Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells." Cell metabolism 15, 1 (2012): 110-21. [PubMed Link] | [ Full text ]
Yuneva, MO ;Fan, TW ;Allen, TD ;Higashi, RM ;Ferraris, DV ;Tsukamoto, T.;Matés, JM ;Alonso, FJ ;Wang, C.;Seo, Y.;Chen, X.;Bishop, JM "The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type." Cell metabolism 15, 2 (2012): 157-70. [PubMed Link] | [ Full text ]
Mattingly, SJ ;Xu, T.;Nantz, MH ;Higashi, RM ;Fan, TW "A Carbonyl Capture Approach for Profiling Oxidized Metabolites in Cell Extracts." Metabolomics : Official journal of the Metabolomic Society 8, 6 (2012): 989-996. [PubMed Link] |
Lorkiewicz, P.;Higashi, RM ;Lane, AN ;Fan, TW "High information throughput analysis of nucleotides and their isotopically enriched isotopologues by direct-infusion FTICR-MS." Metabolomics : Official journal of the Metabolomic Society 8, 5 (2012): 930-939. [PubMed Link] |
Gracey, AY ;Lee, TH ;Higashi, RM ;Fan, T. "Hypoxia-induced mobilization of stored triglycerides in the euryoxic goby Gillichthys mirabilis." The Journal of experimental biology 214, Pt 18 (2011): 3005-12. [PubMed Link] | [ Full text ]
Moseley, HN ;Lane, AN ;Belshoff, AC ;Higashi, RM ;Fan, TW "A novel deconvolution method for modeling UDP-N-acetyl-D-glucosamine biosynthetic pathways based on (13)C mass isotopologue profiles under non-steady-state conditions." BMC biology 9, (2011): 37. [PubMed Link] | [ Full text ]
Lane, AN ;Fan, TW ;Bousamra M, 2nd ;Higashi, RM ;Yan, J.;Miller, DM "Stable isotope-resolved metabolomics (SIRM) in cancer research with clinical application to nonsmall cell lung cancer." Omics : a journal of integrative biology 15, 3 (2011): 173-82. [PubMed Link] |
Muenyi, CS ;States, VA ;Masters, JH ;Fan, TW ;Helm, CW ;States, JC "Sodium arsenite and hyperthermia modulate cisplatin-DNA damage responses and enhance platinum accumulation in murine metastatic ovarian cancer xenograft after hyperthermic intraperitoneal chemotherapy (HIPEC)." Journal of ovarian research 4, (2011): 9. [PubMed Link] | [ Full text ]
Fan, TW ;Lane, AN ;Higashi, RM ;Yan, J. "Stable isotope resolved metabolomics of lung cancer in a SCID mouse model." Metabolomics : Official journal of the Metabolomic Society 7, 2 (2011): 257-269. [PubMed Link] |
Fan, TW ;Lane, AN "NMR-based stable isotope resolved metabolomics in systems biochemistry." Journal of biomolecular NMR 49, 3-4 (2011): 267-80. [PubMed Link] | [ Full text ]
Selivanov, VA ;Vizán, P.;Mollinedo, F.;Fan, TW ;Lee, PW ;Cascante, M. "Edelfosine-induced metabolic changes in cancer cells that precede the overproduction of reactive oxygen species and apoptosis." BMC systems biology 4, (2010): 135. [PubMed Link] | [ Full text ]
Fan, TW ;Yuan, P.;Lane, AN ;Higashi, RM ;Wang, Y.;Hamidi, AB ;Zhou, R.;Guitart, X.;Chen, G.;Manji, HK ;Kaddurah-Daouk, R. "Stable isotope-resolved metabolomic analysis of lithium effects on glial-neuronal metabolism and interactions." Metabolomics : Official journal of the Metabolomic Society 6, 2 (2010): 165-179. [PubMed Link] |
Lane, AN ;Fan, TW ;Xie, Z.;Moseley, HN ;Higashi, RM "Isotopomer analysis of lipid biosynthesis by high resolution mass spectrometry and NMR." Analytica chimica acta 651, 2 (2009): 201-8. [PubMed Link] | [ Full text ]
Fan, TW ;Lane, AN ;Higashi, RM ;Farag, MA ;Gao, H.;Bousamra, M.;Miller, DM "Altered regulation of metabolic pathways in human lung cancer discerned by (13)C stable isotope-resolved metabolomics (SIRM)." Molecular cancer 8, (2009): 41. [PubMed Link] | [ Full text ]
Lane, AN ;Fan, TW ;Higashi, RM ;Tan, J.;Bousamra, M.;Miller, DM "Prospects for clinical cancer metabolomics using stable isotope tracers." Experimental and molecular pathology 86, 3 (2009): 165-73. [PubMed Link] | [ Full text ]
Fan, TW ;Lane, AN ;Higashi, RM ;Bousamra M, 2nd ;Kloecker, G.;Miller, DM "Metabolic profiling identifies lung tumor responsiveness to erlotinib." Experimental and molecular pathology 87, 1 (2009): 83-6. [PubMed Link] | [ Full text ]
Fan, TW ;Kucia, M.;Jankowski, K.;Higashi, RM ;Ratajczak, J.;Ratajczak, MZ ;Lane, AN "Rhabdomyosarcoma cells show an energy producing anabolic metabolic phenotype compared with primary myocytes." Molecular cancer 7, (2008): 79. [PubMed Link] | [ Full text ]
McNeely, SC ;Belshoff, AC ;Taylor, BF ;Fan, TW ;McCabe MJ, Jr ;Pinhas, AR ;States, JC "Sensitivity to sodium arsenite in human melanoma cells depends upon susceptibility to arsenite-induced mitotic arrest." Toxicology and applied pharmacology 229, 2 (2008): 252-61. [PubMed Link] | [ Full text ]
Lane, AN ;Fan, TW ;Higashi, RM "Stable isotope-assisted metabolomics in cancer research." IUBMB life 60, 2 (2008): 124-9. [PubMed Link] | [ Full text ]
Fan, T.;Elgourt, T. "Pain management pharmacy service in a community hospital." American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 65, 16 (2008): 1560-5. [PubMed Link] | [ Full text ]
Lane, AN ;Fan, TW ;Higashi, RM "Isotopomer-based metabolomic analysis by NMR and mass spectrometry." Methods in cell biology 84, (2008): 541-88. [PubMed Link] | [ Full text ]
Sumner, LW ;Amberg, A.;Barrett, D.;Beale, MH ;Beger, R.;Daykin, CA ;Fan, TW ;Fiehn, O.;Goodacre, R.;Griffin, JL ;Hankemeier, T.;Hardy, N.;Harnly, J.;Higashi, R.;Kopka, J.;Lane, AN ;Lindon, JC ;Marriott, P.;Nicholls, AW ;Reily, MD ;Thaden, JJ ;Viant, MR "Proposed minimum reporting standards for chemical analysis Chemical Analysis Working Group (CAWG) Metabolomics Standards Initiative (MSI)." Metabolomics : Official journal of the Metabolomic Society 3, 3 (2007): 211-221. [PubMed Link] |
Podrabsky, JE ;Lopez, JP ;Fan, TW ;Higashi, R.;Somero, GN "Extreme anoxia tolerance in embryos of the annual killifish Austrofundulus limnaeus: insights from a metabolomics analysis." The Journal of experimental biology 210, Pt 13 (2007): 2253-66. [PubMed Link] | [ Full text ]
MSI Board, Members. ;Sansone, SA ;Fan, T.;Goodacre, R.;Griffin, JL ;Hardy, NW ;Kaddurah-Daouk, R.;Kristal, BS ;Lindon, J.;Mendes, P.;Morrison, N.;Nikolau, B.;Robertson, D.;Sumner, LW ;Taylor, C.;Werf, M.;Ommen, B.;Fiehn, O. "The metabolomics standards initiative." Nature biotechnology 25, 8 (2007): 846-8. [PubMed Link] | [ Full text ]
Rose, WL ;Nisbet, RM ;Green, PG ;Norris, S.;Fan, T.;Smith, EH ;Cherr, GN ;Anderson, SL "Using an integrated approach to link biomarker responses and physiological stress to growth impairment of cadmium-exposed larval topsmelt." Aquatic toxicology (Amsterdam, Netherlands) 80, 3 (2006): 298-308. [PubMed Link] | [ Full text ]
Fan, TW ;Higashi, RM ;Lane, AN "Integrating metabolomics and transcriptomics for probing SE anticancer mechanisms." Drug metabolism reviews 38, 4 (2006): 707-32. [PubMed Link] | [ Full text ]
Teh, SJ ;Deng, X.;Deng, DF ;Teh, FC ;Hung, SS ;Fan, TW ;Liu, J.;Higashi, RM "Chronic effects of dietary selenium on juvenile Sacramento splittail (Pogonichthys macrolepidotus)." Environmental science & technology 38, 22 (2004): 6085-93. [PubMed Link] |
Fan, TW ;Lane, AN ;Higashi, RM "An electrophoretic profiling method for thiol-rich phytochelatins and metallothioneins." Phytochemical analysis : PCA 15, 3 (2004): 175-83. [PubMed Link] | [ Full text ]
Fan, TW ;Lane, AN ;Higashi, RM "The promise of metabolomics in cancer molecular therapeutics." Current opinion in molecular therapeutics 6, 6 (2004): 584-92. [PubMed Link] |
Ramos, A.;Lane, AN ;Hollingworth, D.;Fan, TW "Secondary structure and stability of the selenocysteine insertion sequences (SECIS) for human thioredoxin reductase and glutathione peroxidase." Nucleic acids research 32, 5 (2004): 1746-55. [PubMed Link] | [ Full text ]
Fan, TW ;Teh, SJ ;Hinton, DE ;Higashi, RM "Selenium biotransformations into proteinaceous forms by foodweb organisms of selenium-laden drainage waters in California." Aquatic toxicology (Amsterdam, Netherlands) 57, 1-2 (2002): 65-84. [PubMed Link] | [ Full text ]