In a recent article in the journal Nature Biotechnology, University of Kentucky Assistant Professor Nathan Vanderford and doctoral candidate Heather Norman-Burgdolf describe a course developed to help graduate students and postdoctoral fellows be prepared for the realities of the job market. Every year, doctoral graduates enter the job market in search of tenure-track professorship positions at universities throughout the world. Unfortunately, the number of new Ph.D. recipients increases each year while openings for current and new professors fail to keep pace. As a result, it often takes years for many doctoral graduates to land a tenure-track position at a... FULL STORY
Led by Drs. David Orren and Amrita Machwe of the Department of Toxicology and Cancer Biology and the Markey Cancer Center and conducted jointly by recent Ph.D. graduate Deanna Edwards and Dr. Machwe, this article was published online in the September 30 issue of the prestigious, interdisciplinary scientific journal Nature Communications. The research clarifies a putative telomeric maintenance function for the WRN protein that is defective in the cancer-prone and premature aging hereditary disease, Werner syndrome. Located at the ends of each chromosome, telomeres are critical for maintaining genome stability. Conversely, telomere dysfunction during... FULL STORY
Students and Faculty in the Department of Toxicology and Cancer Biology held an Open House in August to meet with incoming first year graduate students. Oral and poster presentations highlighted the varied research programs in the department that investigate basic, translational and clinical aspects of toxicology and cancer biology.
Dr. Donghern Kim is selected 2nd place winner of the Metals Specialty Section Student Award in the Postdoctoral Scholar category for abstract “Chronic Exposure to Hexavalent Chromium Induced Angiogenesis via Activation of EGFR Signaling”, 54th annual meeting of Society of Toxicology, March 22-26, 2015, San Diego, CA.
What if a failed leukemia drug could reduce the risk of Alzheimer’s disease? A team at the University of Kentucky recently led an effort to investigate this hypothesis. Their results were published today in the journal, Human Molecular Genetics. The UK researchers, led by Steve Estus at the Sanders-Brown Center on Aging, study a genetic variant in a gene called CD33 that reduces the risk of Alzheimer’s disease. The Estus group recently published findings suggesting that this variant promotes production of a truncated form of the CD33 protein that lacks a putative functional domain. The CD33 protein is present on microglia, the resident immune cells of the brain. CD33... FULL STORY
Nathan Vanderford, assistant director for research at the University of Kentucky Markey Cancer Center and assistant professor in the Department of Toxicology and Cancer Biology, has a featured article on graduate education in the March 5 edition of Nature. Nature is one of the most prominent and prestigious interdisciplinary scientific journals in the world. Vanderford co-wrote an article titled, "Wanted: Information" with Viviane Callier from the Ronin Institute for Independent Scholarship. In the piece, Vanderford and Callier examine why recent doctoral graduates are having trouble obtaining jobs. They note that doctoral students, specifically those in the science... FULL STORY
Mary Vore was recently awarded the 2014 William R. Willard Award. This award is the College’s highest honor given to individuals who have made singular contributions to the College’s missions in research, teaching and service. Educated at Asbury College, Mary obtained her Ph.D. in pharmacology at Vanderbilt University. She returned to Kentucky as an Assistant Professor in the Department of Pharmacology and rose through the ranks to Professor in 1986. Beginning with her role as Vice-Chair, Mary displayed her administrative abilities and subsequently held a number of other positions leading up to her current roles as Director of the Graduate Center for Toxicology... FULL STORY
Growing up in the small rural town of Paintsville, Kentucky, Hilaree Frazier always loved science. She remembers that from a young age she was interested in pursing a PhD in science, but when she finished her bachelors of science at Eastern Kentucky University (EKU), she was intimidated by the prospect of going straight into a doctoral program. Even though she was interested in UK's Integrated Biomedical Sciences PhD program, she didn't apply. "I think I just didn't have enough confidence," she said. "There weren't a lot of opportunities in science in my hometown." Her undergraduate advisor at EKU suggested that she apply to a program a called the Kentucky Bridge... FULL STORY
The University of Kentucky Markey Cancer Center and the Leukemia and Lymphoma Society hosted their third annual "Meet the Researchers Day" on Tuesday. Meet the Researchers Day is a field trip given as a prize to two schools in the region who successfully raise more than $1,000 for the LLS's Pennies for Patients campaign. This year, students from Meece Middle School (MMS) in Somerset, Ky., and Lexington Traditional Magnet School (LTMS) won the opportunity to visit the Biomedical/Biological Sciences Research Building (BBSRB) on UK's campus and learned more about how the money they raised for Pennies for Patients will help further cancer research. After a formal... FULL STORY
The University of Kentucky Chapter of the International Federation of Medical Student Associations (IFMSA) will host the 10th annual Art of Healing silent auction on Wednesday, April 2. The auction will be held in Biological and Biomedical Sciences Research Building (BBSRB) atrium from noon to 5 p.m. Winning bidders may pick up their art from 5 p.m. to 6 p.m. The auction items feature the handiwork of local and international artists and current students, including pottery, paintings, wood carvings, and accessories. Proceeds from the art auction benefit the Shoulder to Shoulder clinic in Ecuador. Shoulder to Shoulder, an initiative supported by many of the... FULL STORY
Congratulations to Joanne Collazo for passing her Ph.D. defense on Wednesday, 11/26/2013!
Everyone wants to be home for the holidays. Unfortunately, hospital patients don't have that luxury. For those who are unable to enjoy the comforts of a holiday at home, the UK Arts in Healthcare program has scheduled a series of events to help bring the holidays to the hospital. Carolers, pianists, harpists and more will bring holiday cheer to patients, visitors and staff in December. Of particular note: UK HealthCare's own Dr. Jay Zwischenberger will be performing at 1 p.m., Dec. 12, in the Pavilion A of UK Chandler Hospital. Carolers from Deep Springs Elementary School will be performing at noon, Dec.13, Pavilion A of UK Chandler Hospital. Carolers from the... FULL STORY